Nexus Copy Number software offers simple yet powerful tools for CGH and CGH/LOH analysis and visualization of NimbleGen microarrays. Best-in-class algorithms are incorporated into an intuitive, easy-to-use workflow for robust and straightforward analysis. Maximize your time with a user-interface and statistical tools that detect chromosomal aberrations and identify affected pathways in just a few clicks.

Numerous specialized tools are available for researchers to go quickly from raw data to discovery. Powerful cancer specific algorithms provide for ploidy of samples as well as percent contamination with normal cells. Matched tumor/normal paired analysis allows identification of aberrations specific to the tumor sample. Survival analysis tools allow identification of regions highly predictive of survival and generation of Kaplan Meier curves. Integration with gene expression data helps identify "hot spots" of genomic change in the genome.

• Intuitive interface enables advanced research analysis. Simple interface provides a comprehensive, easy-to-use software to quickly go from raw data to advanced analysis for NimbleGen CGH catalog and custom arrays.
• Powerful statistical analysis at your fingertips. Review statistical aberration detection algorithms, plus use the Allele Specific Computation module to process B-allele frequency results and reporting for detection of loss of heterozygosity (LOH).
• Process and visualize a myriad of samples in parallel. Multi-sample processing, visualization and analysis with sample annotations allows you to characterize your research samples for common or rare aberrations using advanced search functions.
• Speed up the time to go from raw data to results. Access to an extensive repository of copy number aberrations allows you to query your region against Nexus DB for instant knowledge of whether such a case was reported by others.

With rich graphics for report ready images, Nexus Copy Number Standard not only speeds up the time to go from raw data to results, but also from results to report. The intuitive interface allows easy visualization and statistical analysis. Nexus Copy Number Discovery offers additional statistical models, data integration, enrichment and clustering analysis specific for large, research data sets.

Figure 1

Figure 1: Nexus Copy Number Standard. This configuration is designed to provide the basic statistical tools for copy number analysis. It allows multi-sample processing, generation of frequency of aberration plots, detection of minimum common regions of gain or loss, and much more.

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