Custom DNA Methylation Arrays
The inherent flexibility of Roche NimbleGen’s array technology enables the rapid prototyping of custom array designs, which can include whole genomes, single chromosomal regions, or multiple loci of interest. Custom designs can be created with uniform or mixed-density probe spacing using the most current genome sequence from any eukaryotic genome.
Learn | Literature
- NEW! NimbleGen ChIP-chip & DNA Methylation Microarrays
Brochure (PDF Format 6MB) - NEW! NimbleGen arrays and LightCycler® 480 System: A complete workflow for DNA methylation biomarker discovery and validation
Application Note (PDF Format 1.7MB) - Guide to Functionally Annotating Your DNA Methylation Data (Version 1.2)
DAVID User’s Guide (PDF Format 274KB)
Find our more about DAVID... - Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
Application Note (PDF Format 914KB)
Learn | Webinars
Dr. Andrew Sharp
Methylation Profiling in Uniparental Tissues Identifies Novel Imprinted Genes
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View Flash MovieDr. Ken Lo
Introducing the NimbleGen ChIP-chip and DNA Methylation Multiplex ArraysDownload MP3Download Video PodcastView Flash MovieDr. A. Leonardo Iniguez
Introducing the High-Resolution, High-Sensitivity NimbleGen 2.1M DNA Methylation ArraysDownload MP3Download Video PodcastView Flash Movie
Learn | Publications
- Aug 2009 | Genome Res
Genome-wide screen of promoter methylation identifies novel markers in melanoma. - Mar 2009 | Development
The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development. - Feb 2009 | Nat Genet
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. - May 2008 | PLoS One
A functional gene array for detection of bacterial virulence elements.
